Thomas S. Vierbuchen: Publications

Thomas S. Vierbuchen: Publications

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Glenn RA, Do SC, Guruvayurappan K, Corrigan EK, Santini L, Medina-Cano D, Singer S, Cho H, Liu J, Broman K, Czechanski A, Reinholdt L, Koche R, Furuta Y, Kunz M, Vierbuchen T.(2024) A PLURIPOTENT STEM CELL PLATFORM FOR IN VITRO SYSTEMS GENETICS STUDIES OF MOUSE DEVELOPMENT. bioRxiv. doi: 10.1101/2024.06.06.597758. 


Medina-Cano D, Corrigan EK, Glenn RA, Islam MT, Lin Y, Kim J, Cho H, Vierbuchen T. (2022) Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids. Development. doi: 10.1242/dev.200561. 

Yang MG, Ling E, Cowley CJ, Greenberg ME, Vierbuchen T. (2022) Characterization of sequence determinants of enhancer function using natural genetic variation. Elife. doi: 10.7554/eLife.76500. 

Marty G Yang, Emi Ling, Christopher J Cowley, Michael E Greenberg, Thomas Vierbuchen. Characterization of sequence determinants of enhancer function using natural genetic variation. eLife 11:e76500. (2022)

Daniel Medina-Cano, Emily K. Corrigan, Rachel A. Glenn, Mohammed T. Islam, Yuan Lin, Juliet Kim, Hyunwoo Cho, Thomas Vierbuchen; Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids. Development 2022; dev.200561. doi: https://doi.org/10.1242/dev.200561

Renthal W*, Boxer LD*, Hrvatin S, Li E, Silberfeld A, Nagy MA, Griffith EC, Vierbuchen T, Greenberg ME. Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing. Nature Neuroscience (in press)

Vierbuchen T*, Ling E*, Cowley C, Couch C, Harmin DA, Wang X, Roberts CW, Greenberg ME. AP-1 transcription factors and the BAF complex mediate signal-dependent enhancer selection. Molecular Cell 68, 1067-1082 (2017)

Mall M, Kareta M, Chanda S, Ahlenius H, Perotti N, Greider S, Ge X, Drake S, Ang CE, Vierbuchen T, Fuentes D et al. Myt1l safeguards neuronal identity by actively repressing non-neuronal fates. Nature 544, 245-249 (2017)

Malik AN*, Vierbuchen T*, Hemberg M, Rubin AA, Ling E, Couch CH, Stroud H, Spiegel I, Farh KK, Harmin DA, Greenberg ME. Genome-wide identification and characterization of functional neuronal activity-dependent enhancers. Nature Neuroscience 10, 1330-39 (2014)

Wapinski OL*, Vierbuchen T*, Qu K, Lee QY, Chanda S, Fuentes D, et al. Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons. Cell 155(3), 621-35 (2013)

Webb AE, Pollina E, Vierbuchen T, Ucar D, Avellaneda NU, Martynoga B, Sewak M, Wernig M, Guillemot F, Brunet A. FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Reports 4(3), 477-91 (2013)

Yang N, Zuchero JB, Ahnlenius H, Marro S, Ng YH, Vierbuchen T, Barres BA, Wernig M. Generation of oligodendroglial cells by direct lineage conversion. Nature Biotechnology 31, 434-439 (2013)

Vierbuchen T, M Wernig. Molecular roadblocks for cellular reprogramming. Molecular Cell 47, 827-838 (2012)

Vierbuchen T, M Wernig. Direct Lineage Conversions: Unnatural but useful? Nature Biotechnology 29, 892-907 (2011)

Pang ZP*, Yang N*, Vierbuchen T* et al. Induction of human neuronal cells by defined transcription factors. Nature 476, 220-223 (2011)

Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof T, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035–1041 (2010)