Heeseon An: Publications

The Heeseon An Lab

Heeseon An: Publications

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19. Yi SA, Sepic S, Schulman BA, Ordureau A, An H* (2024) mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway. Molecular Cell, 84, 1-19.

18. Kim M, Chen C, Yaari Z, Frederiksen R, Randall E, Wollowitz J, Cupo C, Wu X, Shah J, Worroll D, Lagenbacher RE, Goerzen D, Li YM, An H, Wang Y, Heller DA (2023) Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo. Nat. Chem. Biol. Online ahead of print. 

17. Fiesel FC, Fričová D, Hayes CS, Coban MA, Hudec R, Bredenberg JM, Broadway BJ, Markham BN, Yan T, Boneski PK, Fiorino G, Watzlawik JO, Hou X, McCarty AM, Lewis-Tuffin LJ, Zhong J, Madden BJ, Ordureau A, An H, Puschmann A, Wszolek ZK, Ross OA, Harper JW, Caulfield TR, Springer W (2023) Substitution of PINK1 Gly411 modulates substrate receptivity and turnover. Autophagy, 19, 1711-1732.

16. Jordan VN, Ordureau A, An H* (2023) Identifying E3 ligase substrates with quantitative degradation proteomics. ChemBioChem. 37166757.

15. Ordureau A, Kraus F, Zhang J, An H, Park S, Ahfeldt T, Paulo JA, Harper JW (2021) Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy. Mol Cell. 81, 5082-5098

14. Garshott DM, An H, Sundaramoorthy E, Leonard M, Vicary A, Harper JW, Bennett EJ (2021) iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation. Cell Rep. 36, 109642.

13. An H#, Ordureau A#, Koerner M, Paulo JA, Harper JW (2020) Systematic quantitative analysis of ribosome inventory during nutrient stress. Nature, 583, 303-309. # equal contribution

12. Ordureau A, Paulo JA, Zhang J, An H, Swatek KN, Cannon JR, Wan Q, Komander D, Harper JW (2020) Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling. Molecular Cell, 77, 1124-1142.

11. An H, Harper, JW (2020) Ribosome Abundance Control Via the Ubiquitin-Proteasome System and Autophagy. J. Mol. Biol. 432, 170-184, review article

10. An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW (2019) TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress. Molecular Cell, 74, 891-908.

9. An H, Harper JW (2018) Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy. Nat. Cell Biol., 20, 135-143.

8. Juenemann K, Jansen AHP, van Riel L, Merkx R, Mulder MPC, An H, Statsyuk A, Kirstein J, Ovaa H, Reits EA (2018) Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Sci. Rep., 8, 1405.

7. Misra M, Kuhn M, Lobel M, An H, Statsyuk AV, Sotriffer C, Schindelin H (2017) Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure, 25, 1120-1129.

6. An H, Statsyuk AV (2016) Facile synthesis of covalent probes to capture enzymatic intermediates during E1 enzyme catalysis. Chem. Comm., 52, 2477-2480.

5. An H, Statsyuk AV (2015) An inhibitor of ubiquitin conjugation and aggresome formation. Chem. Sci. 6, 5235-5245.

4. An H, Krist D, Statsyuk AV (2014) Crosstalk between kinases and Nedd4 family ubiquitin ligases. Mol. BioSyst., 10, 1643-1657, review article

3. An H, Statsyuk AV (2013) Development of activity-based probes for ubiquitin and ubiquitin-like protein signaling pathways. J. Am. Chem. Soc., 135 (45), 16948-16962.

2. Koh M, Park J, An H, Park SB. (2011) Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry. Chem. Commun. 47, 7614-6.

1. An H, Eum SJ, Koh M, Lee SK, Park SB. (2008) Diversity-oriented synthesis of privileged benzopyranyl heterocycles from s-cis-enones. J. Org. Chem. 2008, 73, 1752-61