Tuomas Tammela: Publications

Tuomas Tammela: Publications

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Singhal A, Styers HC, Rub J, Li Z, Torborg SR, Kim J, Grbovic-Huezo O, Feng H, Tarcan ZC, Sahin Ozkan H, Hallin J, Basturk O, Yaeger R, Christensen JG, Betel D, Yan Y, Chio IIC, de Stanchina E, Tammela T. A classical epithelial state drives acute resistance to KRAS inhibition in pancreas cancer. Cancer Discovery (2024). DOI: 10.1158/2159-8290.CD-24-0740

Zhuang X, Wang Q, Joost S, Ferrena A, Humphreys DT, Li Z, Blum M, Bastl K, Ding S, Landais Y, Zhan Y, Zhao Y, Chaligne R, Lee J, Carrasco SE, Bhanot UK, Koche RP, Bott MJ, Katajisto P, Soto-Feliciano YM, Pisanic T, Thomas T, Zheng D, Wong ES, Tammela T. Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis. bioRxiv [Preprint] 2024.06.23.600305; DOI: 10.1101/2024.06.23.600305

Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg SR, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe S, Rudin CM, Joost S, Tammela T. Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma. Cancer Discovery, 14(2):308–325 (2024). [PMID: 37931288] DOI: 10.1158/2159-8290.CD-23-0289

Torborg SR, Grbovic-Huezo O, Singhal A, Holm M, Wu K, Han X, Ho Y, Haglund C, Mitchell MJ, Lowe SW, Dow LE, Pitter KL, Sanchez-Rivera FJ, Levchenko A, Tammela T. Solid tumor growth depends on an intricate equilibrium of malignant cell states. bioRxiv [Preprint] 2023.12.30.573100; DOI: 10.1101/2023.12.30.573100

Marjanovic ND, Hofree M, Chan JE, Canner D, Wu K, Trakala M, Hartmann GG, Smith OC, Kim JY, Evans KV, Hudson A, Ashenberg O, Porter CBM, Bejnood A, Subramanian A, Pitter K, Yan Y, Delorey T, Phillips DR, Shah N, Chaudhary O, Tsankov A, Hollmann T, Rekhtman N, Massion PP, Poirier JT, Mazutis L, Li R, Lee JH, Amon A, Rudin CM, Jacks T, Regev A, Tammela T. Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell, 38(2):229-246 (2020). DOI: 10.1016/j.ccell.2020.06.012

Tammela T, Sanchez-Rivera FJ, Malli-Cetinbas N, Joshi NS, Helenius K, Park YK, Azimi R, Wu K, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz ÖH, Xue W, Katajisto P, Bhutkar A, Jacks T. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature, 545:355-359 (2017). DOI: 10.1038/nature22334