Molecular Biology Program
The Kenneth Marians Lab
Research
Professor
Research in my laboratory centers on: (i) the events that occur when the replisome (the multi-component enzyme machine that replicates chromosomal DNA) encounters blockages to replication fork progression, and (ii) the mechanisms by which chromosomes are condensed and separated during cell division. Our studies on the consequences of replication fork blockage and restart utilize purified replication, recombination, and transcription proteins in various well-defined systems reconstituted in vitro that model all steps of these events. Our studies on chromosome condensation and segregation utilize a combination of biochemical, cell biological, and molecular genetic approaches.
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Kenneth J. Marians, PhD
William E. Snee Chair
Professor
- Kenneth Marians focuses on mechanisms of replication restart and chromosome segregation.
- PhD, Cornell University
- [email protected]
- Email Address
- 212-639-5890
- Office Phone
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Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
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Kenneth J. Marians discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
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