Dissertation Regulation and heterogeneity of antiviral natural killer cell responses (2019) Mentor Joseph Sun, PhD Start Year 2015 End Year 2019 Education Yale University Fellowships Ruth L. Kirschstein National Research Service Award for Individual Predoctoral MD/PhD Fellows (F30), (2018-2012) Grayer Fellowship (2017-2018) Publications Adams NM, Diaz-Salazar C, Dang C, Lanier LL, Sun JC. (2021) Cutting Edge: Heterogeneity in Cell Age Contributes to Functional Diversity of NK Cells. J Immunol. 206, 465-470 Weizman OE, Song E, Adams NM, Hildreth AD, Riggan L, Krishna C, Aguilar OA, Leslie CS, Carlyle JR, Sun JC, O’Sullivan TE; (2019) Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12. Nat Immunol. 20, 1004-1011. PMCID:PMC6697419. Adams NM, Geary CD, Santosa EK, Lumaquin D, Le Luduec JB, Sottile R, van der Ploeg K, Hsu J, Whitlock BM, Jackson BT, Weizman OE, Huse M, Hsu KC, Sun JC. (2019) Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells. Immunity. pii: S1074-7613(19)30189-X. [Epub ahead of print]. Dong H, Adams NM, Xu Y, Cao J, Allan DSJ, Carlyle JR, Chen X, Sun JC, Glimcher LH; (2019) The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc. Nat Immunol. PMCID: PMC6588410 [Available on 2019-11-13]. Adams NM, Sun JC; (2018) Spatial and temporal coordination of antiviral responses by group 1 ILCs. Immunol Rev. 286, 23-36. PMCID: PMC6178831 [Available on 2019-11-01]. Seelige R, Saddawi-Konefka R, Adams NM, Picarda G, Sun JC, Benedict CA, Bui JD; (2018) Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection. Sci Rep. 8, 13670. PMCID: PMC6135835. Geary CD, Krishna C, Lau CM, Adams NM, Gearty SV, Pritykin Y, Thomsen AR, Leslie CS, Sun JC; (2018) Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection. Cell Rep. 24, 1949-1957. PMCID:PMC6153266. Lau CM, Adams NM, Geary CD, Weizman OE, Rapp M, Pritykin Y, Leslie CS, Sun JC; (2018) Epigenetic control of innate and adaptive immune memory. Nat Immunol. 19, 963-972. PMCID: PMC6225771. Adams NM, Lau CM, Fan X, Rapp M, Geary CD, Weizman OE, Diaz-Salazar C, Sun JC. (2018) Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response. Immunity pii: S1074-7613(18)30187-0. [Epub ahead of print] Rapp M, Lau CM, Adams NM, Weizman OE, O’Sullivan TE, Geary CD, Sun JC; Core-binding factor ß and Runx transcription factors promote adaptive natural killer cell responses.; Science immunology; 2017; 2(18); Weizman OE, Adams NM, Schuster IS, Krishna C, Pritykin Y, Lau C, Degli-Esposti MA, Leslie CS, Sun JC, O’Sullivan TE; ILC1 Confer Early Host Protection at Initial Sites of Viral Infection.; Cell; 2017; 171(4):795-808.e12; O’Sullivan TE, Rapp M, Fan X, Weizman OE, Bhardwaj P, Adams NM, Walzer T, Dannenberg AJ, Sun JC. (2016) Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance. Immunity, 45, 428-41. PMCID: PMC5004886. Adams NM, O’Sullivan TE, Geary CD, Karo JM, Amezquita RA, Joshi NS, Kaech SM, Sun JC. (2016) NK Cell Responses Redefine Immunological Memory. J Immunol. 197, 2963-2970. PMCID: PMC5108457 [Available on 2017-10-15] View a full listing of Nicholas M. Adams’ journal articles.
