Cell Biology Program

The Alban Ordureau Lab

Alban Ordureau, PhD

Assistant Member, Cell Biology Program, SKI; Assistant Professor, Weill Cornell

Assistant Professor

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end, we combine cell biological, genome engineering (CRISPR), and biochemical approaches to provide new insights into mechanisms regulating various aspects of cellular homeostasis. Central to our research efforts, we employ and develop multiple quantitative proteomics workflows to examine how flux in signaling systems (e.g., phosphorylation, ubiquitylation, protein translation, degradation, and trafficking) is altered in response to perturbations or disease mutations.

Publications Highlights

Sinha, N.K., McKenney, C., Yeow, Z.Y.*, Li, J.J.*, Nam, K.H.*, Yaron-Barir, T.M., Johnson, J.L., Huntsman, E.M., Cantley, L.C., Ordureau, A.†, Regot, S.†, Green, R.†. (2024) The ribotoxic stress response drives UV-mediated cell death. Cell, 187(14):3652-3670 (†Co-Corresponding Author)

Ordureau, A.†, Kraus, F., Zhang, J., An, H., Park, S., Ahfeldt, T., Paulo, J.A., Harper, J.W.†. (2021) Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy. Molecular Cell. S1097-2765(21)00800-5.

An, H.*, Ordureau, A.*, Korner, M., Paulo, J.A., Harper, J.W. (2020) Systematic Quantitative Analysis of Ribosome Inventory During Nutrient Stress. Nature 583(7815), 303-309.

Ordureau, A., Paulo, J.A., Zhang, J., An, H., Swatek, K.N., Cannon, J.R., Wan, Q., Komander, D., Harper J.W. (2020) Global landscape and dynamics of Parkin and USP30-dependent ubiquitylomes in iNeurons during mitophagic signaling. Molecular Cell. 77(5):1124-1142.

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People

Alban Ordureau, PhD

Assistant Member, Cell Biology Program, SKI; Assistant Professor, Weill Cornell

Assistant Professor

Alban Ordureau explores molecular signaling pathways that regulate cellular homeostasis, with a focus on the ubiquitin and autophagy systems.
PhD, MRC-PPU - University of Dundee, Scotland, UK
Post-doctoral training - Harvard Medical School, Boston

[email protected]: Email Address
212-639-2284: Office Phone
Download CV: PDF File

Members

Lab Alumni

Lab Affiliations

Achievements

Edward R. and Anne G. Lefler Center Fellow
Pew Biomedical Scholar
Kathryn W. Davis Aging Brain Scholar

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs

Career Opportunities

Applications are invited for Postdoctoral Researchers to work in the laboratory of Alban Ordureau in the Cell Biology Department at Memorial Sloan Kettering Cancer Center (MSK) in New York.

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Get in Touch

[email protected]

Lab Head Email
212-639-2284

Office Phone
212-639-7498

Lab Phone

Lab Resources

To learn more about Postdoc compensation and benefits at MSK, please visit https://www.mskcc.org/education-training/postdoctoral/resources-postdocs/compensation-benefits-resources

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Alban Ordureau discloses the following relationships and financial interests:

Nine Square Therapeutics
Professional Services and Activities

The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].

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