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Large International Study Pinpoints Impact of TP53 Gene Mutations on Blood Cancer Severity Monday, August 3, 2020 Having two mutated copies of the TP53 gene — as opposed to a single mutated copy — is associated with worse outcomes in a blood cancer called myelodysplastic syndrome, according to a new study led by researchers at Memorial Sloan Kettering. 2020 GSK Chairman’s Prize Recognizes Research Exploring New Immunotherapy Approach for Age-Related Inflammatory Diseases Friday, July 31, 2020 Meet Corina Amor Vegas, a fourth-year student in the Gerstner Sloan Kettering Graduate School of Biomedical Sciences (GSK), who has been awarded the 2020 Chairman’s Prize. Finding A Never-Before-Seen Cell State May Explain Cancer’s Ability to Resist Drugs Thursday, July 23, 2020 Identified in mice, this unusual cell state emerges early during tumor evolution and gives tumors enormous malleability. A New Approach in Prostate Cancer: Targeting the Cells Surrounding the Tumor Monday, July 20, 2020 Scientists have found a protein that empowers prostate tumors to resist hormone therapy. The ABCs of BCG: Oldest Approved Immunotherapy Gets New Explanation Friday, July 17, 2020 BCG has been used to treat bladder cancer for more than 30 years. Scientists are still learning how it works. In the Lab Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells Tuesday, June 30, 2020 A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases. In the Lab How Fruit Flies Know When They've Mated Thursday, June 25, 2020 Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies. In the Lab A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target Monday, June 22, 2020 New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma. In the Lab A New Target for CAR T Cells: Senescence-Related Diseases Wednesday, June 17, 2020 From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs. Pagination Load More